Founded in Pisa in 1968 to study the pathophysiology of the cardiovascular system and related organs, the Institute of Clinical Physiology has become a pioneer of the process of “translation” of physiological observations and measurements at molecular and cellular levels towards knowledge, new therapies, guidelines, with positive consequences on the clinical practice and citizens’ health. The staff, accounting for more than 500 employees, includes a multidisciplinary team working on a wide variety of scientific fields, including medicine, biology, physics, chemistry, engineering, computer science, psychology, statistics, etc.
The project aims to simultaneously use different platforms (clinics, bioinformatics, biomechanics ...)
in order to make the genotype/phenotype correlation more reliable in a large cohort of patients
affected by neuromuscular diseases, studied through new generation techniques, thus helping the clinician
in the definition of treatment plans, in monitoring the disease progression and, therefore, in the patients’ care.